BDBM50099645 CHEMBL49689::Thymeleatoxin

SMILES C[C@@H]1[C@@H](OC(=O)\C=C\c2ccccc2)[C@@]2(OC3(O[C@@H]2[C@@H]2C4O[C@]4(CO)[C@@H](O)[C@@]4(O)[C@@H](C=C(C)C4=O)[C@@]12O3)c1ccccc1)C(C)=C

InChI Key InChIKey=OTTFLYUONKAFGT-BSQNJQRESA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50099645   

TargetProtein kinase C delta type(Mus musculus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099645(CHEMBL49689 | Thymeleatoxin)
Affinity DataKi:  2.71nMAssay Description:Displacement of [3H]PDBu from protein kinase C delta C1b domain (Wild type)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Mus musculus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099645(CHEMBL49689 | Thymeleatoxin)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]PDBu from protein kinase C delta C1b domain mutant (F13G)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Mus musculus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099645(CHEMBL49689 | Thymeleatoxin)
Affinity DataKi:  11.3nMAssay Description:Displacement of [3H]PDBu from protein kinase C delta C1b domain mutant (L20G)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Mus musculus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099645(CHEMBL49689 | Thymeleatoxin)
Affinity DataKi:  19.1nMAssay Description:Displacement of [3H]PDBu from protein kinase C delta C1b domain mutant (T12G)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Mus musculus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099645(CHEMBL49689 | Thymeleatoxin)
Affinity DataKi:  47.1nMAssay Description:Displacement of [3H]PDBu from protein kinase C delta C1b domain mutant (Q27V)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Mus musculus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099645(CHEMBL49689 | Thymeleatoxin)
Affinity DataKi:  86.6nMAssay Description:Displacement of [3H]PDBu from protein kinase C delta C1b domain mutant (T8G)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Mus musculus)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50099645(CHEMBL49689 | Thymeleatoxin)
Affinity DataKi:  417nMAssay Description:Displacement of [3H]-PDBu from protein kinase C delta C1b domain mutant (P11G)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed