BDBM50099709 CHEMBL51317::N-(9,10-Dioxo-9,10-dihydro-phenanthren-3-yl)-2-fluoro-benzamide

SMILES Fc1ccccc1C(=O)Nc1ccc2C(=O)C(=O)c3ccccc3-c2c1

InChI Key InChIKey=CWUWDYQQSBBGHE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099709   

TargetReceptor-type tyrosine-protein phosphatase C(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099709(N-(9,10-Dioxo-9,10-dihydro-phenanthren-3-yl)-2-flu...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099709(N-(9,10-Dioxo-9,10-dihydro-phenanthren-3-yl)-2-flu...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10 mer as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099709(N-(9,10-Dioxo-9,10-dihydro-phenanthren-3-yl)-2-flu...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against PTP1B using lck as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed