BDBM50100133 CHEMBL55401::[4-(6-Bromo-benzothiazol-2-yl)-phenyl]-dimethyl-amine

SMILES CN(C)c1ccc(cc1)-c1nc2ccc(Br)cc2s1

InChI Key InChIKey=XTXFRDAVOASSRM-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50100133   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50100133(CHEMBL55401 | [4-(6-Bromo-benzothiazol-2-yl)-pheny...)
Affinity DataKi:  1.90nMAssay Description:Inhibition constant for amyloid beta compared to [125I]-TZDMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50100133(CHEMBL55401 | [4-(6-Bromo-benzothiazol-2-yl)-pheny...)
Affinity DataKi:  1.90nMAssay Description:Inhibition constant for amyloid beta compared to [125I]-TZDMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50100133(CHEMBL55401 | [4-(6-Bromo-benzothiazol-2-yl)-pheny...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50100133(CHEMBL55401 | [4-(6-Bromo-benzothiazol-2-yl)-pheny...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition constant for aggregates of amyloid beta compared to [125I]-IMSBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50100133(CHEMBL55401 | [4-(6-Bromo-benzothiazol-2-yl)-pheny...)
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition constant for aggregates of amyloid beta compared to [125I]-IMSBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed