BDBM50100226 6,7-Dimethoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-2,3-dihydro-1H-quinazolin-4-one::CHEMBL303988

SMILES COc1cccc2[C@@H]3CN(CCN4CNc5cc(OC)c(OC)cc5C4=O)C[C@@H]3CCc12

InChI Key InChIKey=AXGQSWAGPJPUTJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100226   

TargetAlpha-1A adrenergic receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100226(6,7-Dimethoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahy...)
Affinity DataKi:  12.9nMAssay Description:Binding affinity to alpha-1A adrenergic receptor in rat submaxillary glandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100226(6,7-Dimethoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahy...)
Affinity DataKi:  72.0nMAssay Description:Binding affinity of the compound to rat alpha-1D adrenergic receptor expressed in LTK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100226(6,7-Dimethoxy-3-[2-(6-methoxy-1,3,3a,4,5,9b-hexahy...)
Affinity DataKi:  95.2nMAssay Description:Binding affinity to hamster alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed