BDBM50100515 CHEMBL3326305

SMILES Oc1ccc(NS(=O)(=O)c2ccc3NC(=O)c4cccc2c34)cc1Cl

InChI Key InChIKey=FQWAQUPLBBOCSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100515   

TargetTumor necrosis factor(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50100515(CHEMBL3326305)
Affinity DataIC50:  4.57E+4nMAssay Description:Inhibition of TNFalpha (unknown origin) assessed as IkappaB-alpha phosphorylation in Hela cells after 15 mins by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTumor necrosis factor(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50100515(CHEMBL3326305)
Affinity DataIC50:  4.23E+4nMAssay Description:Inhibition of TNFalpha in HEK293T cells transfected with plasmid hRluc/TK/ luc2P/NF-kBRE/Hygro plasmid after 12 hrs by Dual-glo luciferase assay syst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed