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BDBM50101295 4-{(4-Benzyl-piperazin-1-yl)-[(Z)-2-chloro-phenylimino]-methyl}-N,N-diethyl-benzamide::CHEMBL297498

SMILES: CCN(CC)C(=O)c1ccc(cc1)C(=N\c1ccccc1Cl)\N1CCN(Cc2ccccc2)CC1

InChI Key: InChIKey=CWVBENBIHGETOF-PNOGMODKSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50101295   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Opioid receptors; mu & delta


(Rattus norvegicus (rat))
BDBM50101295
PNG
(4-{(4-Benzyl-piperazin-1-yl)-[(Z)-2-chloro-phenyli...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(=N\c1ccccc1Cl)\N1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C29H33ClN4O/c1-3-33(4-2)29(35)25-16-14-24(15-17-25)28(31-27-13-9-8-12-26(27)30)34-20-18-32(19-21-34)22-23-10-6-5-7-11-23/h5-17H,3-4,18-22H2,1-2H3/b31-28-
PDB

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UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
12n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of binding of [3H]-DPDPE to opioid receptor delta 1 from rat brain membrane.


Bioorg Med Chem Lett 11: 1741-3 (2001)


Article DOI: 10.1016/s0960-894x(01)00272-4
BindingDB Entry DOI: 10.7270/Q2PZ59BK
More data for this
Ligand-Target Pair
Nociceptin/mu opioid receptor


(Rattus norvegicus (rat))
BDBM50101295
PNG
(4-{(4-Benzyl-piperazin-1-yl)-[(Z)-2-chloro-phenyli...)
Show SMILES CCN(CC)C(=O)c1ccc(cc1)C(=N\c1ccccc1Cl)\N1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C29H33ClN4O/c1-3-33(4-2)29(35)25-16-14-24(15-17-25)28(31-27-13-9-8-12-26(27)30)34-20-18-32(19-21-34)22-23-10-6-5-7-11-23/h5-17H,3-4,18-22H2,1-2H3/b31-28-
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of binding of [3H]DAMGO to opioid receptor mu 1 from rat brain membrane.


Bioorg Med Chem Lett 11: 1741-3 (2001)


Article DOI: 10.1016/s0960-894x(01)00272-4
BindingDB Entry DOI: 10.7270/Q2PZ59BK
More data for this
Ligand-Target Pair