BDBM50101495 (R)-2-[3-(4-Chloro-phenyl)-propyl]-N*1*-((S)-2-cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4*-hydroxy-succinamide::2-[3-(4-Chloro-phenyl)-propyl]-N*1*-(2-cyclohexyl-1-phenethylcarbamoyl-ethyl)-N*4*-hydroxy-succinamide::CHEMBL311397

SMILES ONC(=O)C[C@@H](CCCc1ccc(Cl)cc1)C(=O)N[C@@H](CC1CCCCC1)C(=O)NCCc1ccccc1

InChI Key InChIKey=OHBYAEPYMITRJA-VPUSJEBWSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50101495   

Target72 kDa type IV collagenase(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101495((R)-2-[3-(4-Chloro-phenyl)-propyl]-N*1*-((S)-2-cyc...)
Affinity DataKi:  0.0300nMAssay Description:Inhibitory constant against matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101495((R)-2-[3-(4-Chloro-phenyl)-propyl]-N*1*-((S)-2-cyc...)
Affinity DataKi:  0.0300nMAssay Description:Inhibition of the gelatinase-A enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101495((R)-2-[3-(4-Chloro-phenyl)-propyl]-N*1*-((S)-2-cyc...)
Affinity DataKi:  7.30nMAssay Description:Inhibition of the stromelysin enzyme.More data for this Ligand-Target Pair
In DepthDetails Article
TargetStromelysin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50101495((R)-2-[3-(4-Chloro-phenyl)-propyl]-N*1*-((S)-2-cyc...)
Affinity DataKi:  7.31nMAssay Description:Inhibitory constant against matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101495((R)-2-[3-(4-Chloro-phenyl)-propyl]-N*1*-((S)-2-cyc...)
Affinity DataKi:  2.44E+3nMAssay Description:Inhibitory constant against matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50101495((R)-2-[3-(4-Chloro-phenyl)-propyl]-N*1*-((S)-2-cyc...)
Affinity DataKi:  2.44E+3nMAssay Description:Inhibition of the collagenase enzyme.More data for this Ligand-Target Pair
In DepthDetails Article