BDBM50101652 5-Acetyl-4-{2-[4-(2-fluoro-phenyl)-piperazin-1-yl]-ethylamino}-2-methyl-6-phenyl-2H-pyridazin-3-one::CHEMBL420205

SMILES CC(=O)c1c(NCCN2CCN(CC2)c2ccccc2F)c(=O)n(C)nc1-c1ccccc1

InChI Key InChIKey=DUFHNVVBRSIXJN-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101652   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101652(5-Acetyl-4-{2-[4-(2-fluoro-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  0.320nMAssay Description:Binding affinity towards human cloned alpha1A-adrenoceptor using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101652(5-Acetyl-4-{2-[4-(2-fluoro-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  0.490nMAssay Description:Binding affinity towards human cloned alpha1d-adrenoceptor using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101652(5-Acetyl-4-{2-[4-(2-fluoro-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  3.77nMAssay Description:Binding affinity towards human cloned alpha1B-adrenoceptor using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101652(5-Acetyl-4-{2-[4-(2-fluoro-phenyl)-piperazin-1-yl]...)
Affinity DataKi:  24.1nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed