BDBM50101662 5-Acetyl-4-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethylamino}-2,6-dimethyl-2H-pyridazin-3-one::CHEMBL77901

SMILES COc1ccccc1N1CCN(CCNc2c(C(C)=O)c(C)nn(C)c2=O)CC1

InChI Key InChIKey=JTNOVHSABZCNCD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101662   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101662(5-Acetyl-4-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  2.29nMAssay Description:Binding affinity towards human cloned alpha1A-adrenoceptor using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101662(5-Acetyl-4-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity towards human cloned alpha1d-adrenoceptor using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101662(5-Acetyl-4-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  13nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101662(5-Acetyl-4-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl...)
Affinity DataKi:  49.8nMAssay Description:Binding affinity towards human cloned alpha1B-adrenoceptor using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed