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BDBM50101744 CHEMBL3394893

SMILES: COc1cc(\C=N\NC(=O)c2ccc(NC(C)=O)nc2)cc(Br)c1O

InChI Key: InChIKey=TZJRTGHDAYCHGF-FBCYGCLPSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50101744   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone chaperone ASF1A


(Homo sapiens)
BDBM50101744
PNG
(CHEMBL3394893)
Show SMILES COc1cc(\C=N\NC(=O)c2ccc(NC(C)=O)nc2)cc(Br)c1O
Show InChI InChI=1S/C16H15BrN4O4/c1-9(22)20-14-4-3-11(8-18-14)16(24)21-19-7-10-5-12(17)15(23)13(6-10)25-2/h3-8,23H,1-2H3,(H,21,24)(H,18,20,22)/b19-7+
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Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Colorado State University

Curated by ChEMBL


Assay Description
Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay


Bioorg Med Chem Lett 25: 963-8 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.067
BindingDB Entry DOI: 10.7270/Q2VM4F0G
More data for this
Ligand-Target Pair