BDBM50102080 (3-Chloro-4-fluoro-phenyl)-[6-(2-dimethylamino-ethoxy)-7-methoxy-quinazolin-4-yl]-amine::CHEMBL57759

SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCN(C)C

InChI Key InChIKey=CBVZLUIKUXDQLU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102080   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50102080((3-Chloro-4-fluoro-phenyl)-[6-(2-dimethylamino-eth...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibitory activity against Epidermal growth factor receptor (EGFR-TK) from A431 vulval squamous carcinoma cells using TKI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed