BDBM50102155 1-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-5-(2-cyclopropyl-pyrimidin-5-ylmethyl)-2-(4-fluoro-benzylsulfanyl)-1H-pyrimidin-4-one::CHEMBL292367

SMILES Fc1ccc(CSc2nc(=O)c(Cc3cnc(nc3)C3CC3)cn2CC(=O)N2CCN(CC2)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=XPMMYQCHISLPJU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102155   

TargetPlatelet-activating factor acetylhydrolase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50102155(1-{2-[4-(4-Chloro-phenyl)-piperazin-1-yl]-2-oxo-et...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against human lipoprotein associated phospholipase A2 (Lp-PLA2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed