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BDBM50102199 2-Methyl-4-{6-[methyl-(2-pyridin-2-yl-ethyl)-amino]-4-phenyl-pyridin-2-yl}-phenol::CHEMBL59271

SMILES: CN(CCc1ccccn1)c1cc(cc(n1)-c1ccc(O)c(C)c1)-c1ccccc1

InChI Key: InChIKey=GREQBSJJGDAHBG-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50102199   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Estrogen receptor


(Homo sapiens (Human))
BDBM50102199
PNG
(2-Methyl-4-{6-[methyl-(2-pyridin-2-yl-ethyl)-amino...)
Show SMILES CN(CCc1ccccn1)c1cc(cc(n1)-c1ccc(O)c(C)c1)-c1ccccc1
Show InChI InChI=1S/C26H25N3O/c1-19-16-21(11-12-25(19)30)24-17-22(20-8-4-3-5-9-20)18-26(28-24)29(2)15-13-23-10-6-7-14-27-23/h3-12,14,16-18,30H,13,15H2,1-2H3
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.26E+3n/an/an/an/an/an/an/an/a



Glaxo Wellcome Research and Development

Curated by ChEMBL


Assay Description
Ability to displace [3H]-17-beta-estradiol from Estrogen receptor alpha by scintillation proximity assay.


Bioorg Med Chem Lett 11: 1939-42 (2001)


Article DOI: 10.1016/s0960-894x(01)00321-3
BindingDB Entry DOI: 10.7270/Q2ZK5FZ0
More data for this
Ligand-Target Pair
Estradiol receptor beta (ERβ)


(Homo sapiens (Human))
BDBM50102199
PNG
(2-Methyl-4-{6-[methyl-(2-pyridin-2-yl-ethyl)-amino...)
Show SMILES CN(CCc1ccccn1)c1cc(cc(n1)-c1ccc(O)c(C)c1)-c1ccccc1
Show InChI InChI=1S/C26H25N3O/c1-19-16-21(11-12-25(19)30)24-17-22(20-8-4-3-5-9-20)18-26(28-24)29(2)15-13-23-10-6-7-14-27-23/h3-12,14,16-18,30H,13,15H2,1-2H3
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
>3.00E+3n/an/an/an/an/an/an/an/a



Glaxo Wellcome Research and Development

Curated by ChEMBL


Assay Description
Ability to displace [3H]-17-beta-estradiol from Estrogen receptor beta by scintillation proximity assay.


Bioorg Med Chem Lett 11: 1939-42 (2001)


Article DOI: 10.1016/s0960-894x(01)00321-3
BindingDB Entry DOI: 10.7270/Q2ZK5FZ0
More data for this
Ligand-Target Pair