BDBM50102325 6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine::CHEMBL340801::Perlapine

SMILES CN1CCN(CC1)C1=Nc2ccccc2Cc2ccccc12

InChI Key InChIKey=PWRPUAKXMQAFCJ-UHFFFAOYSA-N

Data  16 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50102325   

TargetD(4) dopamine receptor(RAT)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  7.90nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  12.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  12.6nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  28nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  30nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  60nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  60nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(RAT)
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  70nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
University Of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  100nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
University Of Washington

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  501nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  501nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
University Of Pennsylvania

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataKi:  919nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Case Western Reserve University

Curated by PDSP Ki Database
LigandPNGBDBM50102325(6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepin...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed