BDBM50102777 2-(5-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-carboxamidine::2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}-4-FLUOROBENZENOLATE::CHEMBL92277

SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1cc(F)ccc1O

InChI Key InChIKey=JOGOACSSLJEREC-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102777   

TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102777(2-(5-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  2.80E+3nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102777(2-(5-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  6.80E+3nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102777(2-(5-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102777(2-(5-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102777(2-(5-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102777(2-(5-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  4.60E+4nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed