BDBM50103503 CHEMBL2393130::US11117865, Compound RVX-208

SMILES: Cc1cc(cc(c1OCCO)C)C2=Nc3cc(cc(c3C(=O)N2)OC)OC

InChI Key: InChIKey=NETXMUIMUZJUTB-UHFFFAOYSA-N

Data: 2 KI  58 IC50  43 Kd

PDB links: 6 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 111 hits for monomerid = 50103503   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [49-170] (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 [342-460] (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 [91-163] (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 [364-436] (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 [51-123] (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 [326-398] (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	203	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein [22-138] (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein [287-359] (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	708	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
CREB-binding protein (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 [34-140] (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.34E+7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.78E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	135	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	251	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.07E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	251	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	203	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.78E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain testis-specific protein (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	708	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
CREB-binding protein (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 2 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	135	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bromodomain-containing protein 3 (Human)	BDBM50103503 (CHEMBL2393130 | US11117865, Compound RVX-208 | US2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair