BDBM50103516 CHEBI:40009::CYCLOSERINE::Cycloserine::Seromycin

SMILES N[C@@H]1CONC1=O

InChI Key InChIKey=DYDCUQKUCUHJBH-UWTATZPHSA-N

Data  4 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50103516   

TargetBile salt export pump(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50103516(CHEBI:40009 | CYCLOSERINE | Cycloserine | Seromyci...)
Show SMILES N[C@@H]1CONC1=O
Show InChI InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptakeMore data for this Ligand-Target Pair
TargetD-alanine--D-alanine ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
Universit£ Catholique de Louvain (UCLouvain)

Curated by ChEMBL
LigandPNGBDBM50103516(CHEBI:40009 | CYCLOSERINE | Cycloserine | Seromyci...)
Show SMILES N[C@@H]1CONC1=O
Show InChI InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
Affinity DataIC50: 2.62E+5nMAssay Description:Inhibition of Enterococcus faecalis JH2-2 C-terminal 6His-tagged DdlB expressed in Escherichia coli LMG194 preincubated for 30 mins followed by subst...More data for this Ligand-Target Pair
TargetBile salt export pump(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50103516(CHEBI:40009 | CYCLOSERINE | Cycloserine | Seromyci...)
Show SMILES N[C@@H]1CONC1=O
Show InChI InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
TargetBile salt export pump(Rattus norvegicus)
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50103516(CHEBI:40009 | CYCLOSERINE | Cycloserine | Seromyci...)
Show SMILES N[C@@H]1CONC1=O
Show InChI InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate up...More data for this Ligand-Target Pair