BDBM50103521 Actos::CHEBI:8228::Duetact::Pioglitazone::US20240091210, Compound Pioglitazone

SMILES: CCc1ccc(nc1)CCOc2ccc(cc2)C[C@@H]3C(=O)NC(=O)S3

InChI Key: InChIKey=HYAFETHFCAUJAY-UHFFFAOYSA-N

Data: 11 KI  21 IC50  2 Kd  32 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 66 hits for monomerid = 50103521   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.77E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	871	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Mitochondrial pyruvate carrier 1/2 (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	298	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	650	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	720	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	575	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Rat)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	380	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	98	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.05E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 1 (Rat)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Mouse)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	970	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
CDGSH iron-sulfur domain-containing protein 2 (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	589	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	871	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Human)	BDBM50103521 (CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	260	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair