BDBM50103596 (E)-2-hydroxy-5-((4-(N-pyridin-2-ylsulfamoyl)-phenyl)diazenyl) benzoic acid (A8)::Azulfidine::Azulfidine EN::Azulfidine EN-Tabs::CHEBI:9334::S.A.S.::S.A.S.-500::SAS-500::Salazopyrin::Salazosulfapyridine::Salicylazosulfapyridine::Sulfasalazine::Sulphasalazine::US11744839, Compound of formula 1

SMILES: c1ccnc(c1)NS(=O)(=O)c2ccc(cc2)/N=N/c3ccc(c(c3)C(=O)O)O

InChI Key: InChIKey=NCEXYHBECQHGNR-UHFFFAOYSA-N

Data: 1 KI  12 IC50  5 Kd  1 EC50  1 ITC

PDB links: 6 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50103596   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/bile acid cotransporter (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2J2 (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium/bile acid cotransporter (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sodium/bile acid cotransporter (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Broad substrate specificity ATP-binding cassette transporter ABCG2 (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
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Flavin reductase (NADPH) (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	437	n/a	n/a	n/a	n/a	n/a
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Flavin reductase (NADPH) (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	916	n/a	n/a	n/a	n/a
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Tumor necrosis factor (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.00E+3	n/a	n/a	n/a	7.0	n/a
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Replicase polyprotein 1ab (MERS-CoV)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a
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Cystine/glutamate transporter (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cystine/glutamate transporter (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cystine/glutamate transporter (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.46E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Flavin reductase (NADPH) (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a
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Bifunctional purine biosynthesis protein ATIC (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...) Show SMILES Show InChI	GoogleScholar	UniChem		2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 50103596

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
Flavin reductase (NADPH) (Human)	BDBM50103596 (CHEBI:9334 | Azulfidine | Azulfidine EN | Azulfidi...)	GoogleScholar			-8.67	0.783	-9.43	6.36	n/a	25
TBA					Details of this binding reaction