BDBM50103621 A-61589::AA-861::CHEBI:2340::Docebenone
SMILES CC1=C(C)C(=O)C(CCCCC#CCCCC#CCO)=C(C)C1=O
InChI Key InChIKey=WDEABJKSGGRCQA-UHFFFAOYSA-N
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50103621
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
National Institutes Of Health Chemical Genomics Center
Curated by ChEMBL
National Institutes Of Health Chemical Genomics Center
Curated by ChEMBL
Affinity DataEC50: 2.82E+4nMAssay Description:Activation of human PXR expressed in human HepG2 (DPX-2) cells after 24 hrs by luciferase reporter gene based luminescent analysisMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
National Institutes Of Health Chemical Genomics Center
Curated by ChEMBL
National Institutes Of Health Chemical Genomics Center
Curated by ChEMBL
Affinity DataEC50: 1.26E+4nMAssay Description:Competitive binding affinity to human PXR LBD (111 to 434) by TR-FRET assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
National Institutes Of Health Chemical Genomics Center
Curated by ChEMBL
National Institutes Of Health Chemical Genomics Center
Curated by ChEMBL
Affinity DataEC50: 7.10E+3nMAssay Description:Activation of human PXR expressed in human HepG2 (DPX-2) cells assessed as induction of CYP3A4 after 24 hrs by luminescent analysisMore data for this Ligand-Target Pair