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BDBM50103730 5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-3-carboxylic acid (3-iodo-phenyl)-amide::CHEMBL74777

SMILES: Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1cccc(I)c1

InChI Key: InChIKey=DYYSCQNGKZJJCO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50103730   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuropeptide Y receptor type 5 ( NPY Y5)


(Homo sapiens (Human))
BDBM50103730
PNG
(5-Methyl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-...)
Show SMILES Cc1cc(nn1-c1cccc(c1)C(F)(F)F)C(=O)Nc1cccc(I)c1
Show InChI InChI=1S/C18H13F3IN3O/c1-11-8-16(17(26)23-14-6-3-5-13(22)10-14)24-25(11)15-7-2-4-12(9-15)18(19,20)21/h2-10H,1H3,(H,23,26)
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 670n/an/an/an/an/an/a



The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity to human neuropeptide Y receptor type 5 (NPY5) in HEK 293 cell line assayed by using [125I]-PYY as radioligand


Bioorg Med Chem Lett 11: 2287-90 (2001)


Article DOI: 10.1016/s0960-894x(01)00449-8
BindingDB Entry DOI: 10.7270/Q2J67G6S
More data for this
Ligand-Target Pair