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BDBM50103837 7-[4-(4-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-yl]-3H-benzooxazol-2-one::CHEMBL77334

SMILES: Fc1ccc(cc1CN1CCN(CC1)c1cccc2[nH]c(=O)oc12)-c1ccccc1

InChI Key: InChIKey=YTLARIHDMMQLCL-UHFFFAOYSA-N

Data: 2 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50103837   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50103837
PNG
(7-[4-(4-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-yl...)
Show SMILES Fc1ccc(cc1CN1CCN(CC1)c1cccc2[nH]c(=O)oc12)-c1ccccc1
Show InChI InChI=1S/C24H22FN3O2/c25-20-10-9-18(17-5-2-1-3-6-17)15-19(20)16-27-11-13-28(14-12-27)22-8-4-7-21-23(22)30-24(29)26-21/h1-10,15H,11-14,16H2,(H,26,29)
PDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
12n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Binding affinity for dopamine receptor D2 determined using [3H]-spiperone


Bioorg Med Chem Lett 11: 2345-9 (2001)


Article DOI: 10.1016/s0960-894x(01)00425-5
BindingDB Entry DOI: 10.7270/Q2RR1XH9
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))
BDBM50103837
PNG
(7-[4-(4-Fluoro-biphenyl-3-ylmethyl)-piperazin-1-yl...)
Show SMILES Fc1ccc(cc1CN1CCN(CC1)c1cccc2[nH]c(=O)oc12)-c1ccccc1
Show InChI InChI=1S/C24H22FN3O2/c25-20-10-9-18(17-5-2-1-3-6-17)15-19(20)16-27-11-13-28(14-12-27)22-8-4-7-21-23(22)30-24(29)26-21/h1-10,15H,11-14,16H2,(H,26,29)
UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
41n/an/an/an/an/an/an/an/a



Solvay Pharma

Curated by ChEMBL


Assay Description
Binding affinity for 5-hydroxytryptamine 1A receptor determined using [3H]-8-OH-DPAT as radioligand


Bioorg Med Chem Lett 11: 2345-9 (2001)


Article DOI: 10.1016/s0960-894x(01)00425-5
BindingDB Entry DOI: 10.7270/Q2RR1XH9
More data for this
Ligand-Target Pair