BDBM50104381 4-[5-(4-Fluoro-phenyl)-3-methyl-2-(4-methylsulfanyl-phenyl)-3H-imidazol-4-yl]-pyridine::CHEMBL88045

SMILES CSc1ccc(cc1)-c1nc(c(-c2ccncc2)n1C)-c1ccc(F)cc1

InChI Key InChIKey=BJXGEYDZUISYLS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50104381   

TargetMitogen-activated protein kinase 11/12/13/14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104381(4-[5-(4-Fluoro-phenyl)-3-methyl-2-(4-methylsulfany...)
Affinity DataIC50: 520nMAssay Description:Binding affinity towards human Mitogen-activated protein kinase p38 expressed as IC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlucagon receptor(Human)TBA
LigandPNGBDBM50104381(4-[5-(4-Fluoro-phenyl)-3-methyl-2-(4-methylsulfany...)
Affinity DataIC50: 521nMAssay Description:Inhibition of human glucagon receptor expressed in CHO cell membranes by radioligand displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article