BindingDB logo
myBDB logout

BDBM50104474 CHEMBL262163::Phosphoric acid 12-[(R)-2-amino-3-(1H-indol-3-yl)-propionylamino]-dodecyl ester 2-chloro-phenyl ester; compound with triethyl-amine

SMILES: N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl

InChI Key: InChIKey=WFSUUCMFXNYGLO-AREMUKBSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50104474   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens (Human))
BDBM50104474
PNG
(CHEMBL262163 | Phosphoric acid 12-[(R)-2-amino-3-(...)
Show SMILES N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCCCCCCCCCCCCOP(O)(=O)Oc1ccccc1Cl
Show InChI InChI=1S/C29H41ClN3O5P/c30-25-16-10-12-18-28(25)38-39(35,36)37-20-14-8-6-4-2-1-3-5-7-13-19-32-29(34)26(31)21-23-22-33-27-17-11-9-15-24(23)27/h9-12,15-18,22,26,33H,1-8,13-14,19-21,31H2,(H,32,34)(H,35,36)/t26-/m1/s1
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.52E+4n/an/an/an/an/an/a



Kyushu University

Curated by ChEMBL


Assay Description
Inhibitory activity against telomerase extracted from HCT 116 cell lines


Bioorg Med Chem Lett 11: 2581-4 (2001)


Article DOI: 10.1016/s0960-894x(01)00507-8
BindingDB Entry DOI: 10.7270/Q2XD10Z2
More data for this
Ligand-Target Pair