BDBM50104501 (R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid ((S)-1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amide::(R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid ((S)-1-dimethylcarbamoyl-2-methyl-2-methyl-propyl)-amide::(R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid (1-dimethylcarbamoyl-2,2-dimethyl-propyl)-amide::(R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic acid [1-((S)-dimethyl-carbamoyl)-2,2-dimethyl-propyl]-amide::2-[(FORMYL-HYDROXY-AMINO)-METHYL]-HEXANOIC ACID (1-DIMETHYLCARBAMOYL-2,2-DIMETHYL-PROPYL)-AMIDE::BB-3497::CHEMBL431210

SMILES CCCC[C@H](CN(O)C=O)C(=O)N[C@H](C(=O)N(C)C)C(C)(C)C

InChI Key InChIKey=AVDLWYHBABSSHC-CHWSQXEVSA-N

Data  1 KI  12 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50104501   

TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataKi:  11nMAssay Description:Inhibitory effect against E. coli peptide deformylase (PDF) by DPPI assayMore data for this Ligand-Target Pair
TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against Escherichia coli peptide deformylase (PDF) Nickel containing enzymeMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50: >1.00E+5nMAssay Description:Compound was tested for its inhibitory activity against Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  5.00E+4nMAssay Description:The compound was evaluated in vitro for the inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  7nMAssay Description:Antibacterial activity of the compound against E. coli Peptide deformylase. NiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  7nMAssay Description:Inhibition concentration against Escherichia coli peptide deformylase.More data for this Ligand-Target Pair
TargetMatrilysin(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  7nMAssay Description:Compound was evaluated for inhibition of peptide deformylase, PDF.Ni of Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase, mitochondrial(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  7nMAssay Description:Inhibition against Escherichia coli peptide deformylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPeptide deformylase(Escherichia coli)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  7nMAssay Description:Inhibition concentration against Escherichia coli peptide deformylase.More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104501((R)-2-[(Formyl-hydroxy-amino)-methyl]-hexanoic aci...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed