BDBM50104970 CHEMBL114357::N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-(3-methoxy-benzyl)-succinamide

SMILES COc1cccc(C[C@H](CC(=O)NO)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)c1

InChI Key InChIKey=ZFCJDZRVAOLEGY-ZTNFWEORSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50104970   

TargetNeutrophil collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104970(CHEMBL114357 | N*4*-Hydroxy-N*1*-(2-hydroxy-indan-...)
Affinity DataKi:  1.19E+3nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104970(CHEMBL114357 | N*4*-Hydroxy-N*1*-(2-hydroxy-indan-...)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104970(CHEMBL114357 | N*4*-Hydroxy-N*1*-(2-hydroxy-indan-...)
Affinity DataKi:  1.55E+4nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104970(CHEMBL114357 | N*4*-Hydroxy-N*1*-(2-hydroxy-indan-...)
Affinity DataKi:  9.55E+4nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed