BDBM50105045 4-tert-Butyl-N-{5-(3-methoxy-phenoxy)-6-[2-(pyrimidin-2-yloxy)-ethylamino]-pyrimidin-4-yl}-benzenesulfonamide; compound with methane::CHEMBL442031

SMILES COc1cccc(Oc2c(NCCOc3ncccn3)ncnc2NS(=O)(=O)c2ccc(cc2)C(C)(C)C)c1

InChI Key InChIKey=JBEKJJLVSSCNMS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105045   

TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105045(4-tert-Butyl-N-{5-(3-methoxy-phenoxy)-6-[2-(pyrimi...)
Affinity DataIC50:  6.20nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
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