BDBM50105076 8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL115280

SMILES: O=C1NCN(c2ccccc2)C11CCN(Cc2cccc(Oc3ccccc3)c2)CC1

InChI Key: InChIKey=SKVXOYIMICHFPV-UHFFFAOYSA-N

Data: 17 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50105076   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent noradrenaline transporter (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Nociceptin receptor (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mu-type opioid receptor (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
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Muscarinic acetylcholine receptor M2 (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(2) dopamine receptor (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	538	n/a	n/a	n/a	n/a	n/a	n/a
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Histamine H1 receptor (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	496	n/a	n/a	n/a	n/a	n/a	n/a
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Sodium-dependent dopamine transporter (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sigma non-opioid intracellular receptor 1 (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Kappa-type opioid receptor (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
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Delta-type opioid receptor (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-1 adrenergic receptor (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
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D(3) dopamine receptor (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Delta-type opioid receptor (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Voltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	552	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Mu-type opioid receptor (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Human)	BDBM50105076 (8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair