BDBM50105087 4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-carboxylic acid (benzo[1,3]dioxol-5-ylmethyl)-amide::CHEMBL113811

SMILES O=C(NCc1ccc2OCOc2c1)N1CCC2(CC1)N(CNC2=O)c1ccccc1

InChI Key InChIKey=IJVGQGLSIIVNAQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105087   

TargetKappa-type opioid receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105087(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...)
Affinity DataIC50: 2.28E+3nMAssay Description:Binding affinity against opioid receptor kappa 1 by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105087(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...)
Affinity DataIC50: 2.28E+3nMAssay Description:Binding affinity against opioid receptor kappa 1 using [3H]- U-69,593 radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105087(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Universities of Lille

Curated by ChEMBL
LigandPNGBDBM50105087(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]decane-8-car...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against delta-opiate receptor (human) using [3H]-DPDPE radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed