BDBM50105106 1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,3-dihydro-benzoimidazol-2-one::CHEMBL114484

SMILES Cc1ccc(CN2CCC(CC2)n2c3ccccc3[nH]c2=O)c(Cl)c1

InChI Key InChIKey=KTQASNDGWLUTPN-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50105106   

TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50:  1.34E+3nMAssay Description:Binding affinity against L-type calcium channel verapamil siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50:  1.41E+3nMAssay Description:Inhibition of ligand binding to human delta opioid receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of alpha-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50:  480nMAssay Description:Inhibition of human dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50:  1.57E+3nMAssay Description:Binding affinity against muscarinic acetylcholine receptor M2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50:  154nMAssay Description:Inhibition of human dopamine receptor D3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50:  16nMAssay Description:Binding affinity against mu opiate receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50:  1.78E+3nMAssay Description:Binding affinity against M1 muscarinic receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50:  849nMAssay Description:Inhibition of human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50:  1.91E+3nMAssay Description:Inhibition of human ORL1 orphanin receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50:  270nMAssay Description:Binding affinity against opioid receptor kappa 1 by using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50:  1.69E+3nMAssay Description:Inhibition of human dopamine receptor D4.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Universities Of Lille

Curated by ChEMBL
LigandPNGBDBM50105106(1-[1-(2-Chloro-4-methyl-benzyl)-piperidin-4-yl]-1,...)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of human dopamine receptor D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed