BDBM50105243 6,7-Dimethoxy-2-methyl-1,1-dioxo-1,2,3,4-tetrahydro-1lambda*6*-benzo[e][1,2]thiazine-3-carboxylic acid (1-benzyl-2-oxo-ethyl)-amide::CHEMBL332683

SMILES COc1cc2CC(N(C)S(=O)(=O)c2cc1OC)C(=O)N[C@@H](Cc1ccccc1)C=O

InChI Key InChIKey=RVMZUHOZKYCBJC-BHWOMJMDSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105243   

TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50105243(6,7-Dimethoxy-2-methyl-1,1-dioxo-1,2,3,4-tetrahydr...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity towards human calpain IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50105243(6,7-Dimethoxy-2-methyl-1,1-dioxo-1,2,3,4-tetrahydr...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibitory concentration against MOLT-4 cells (human T-cell leukemia cell line)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50105243(6,7-Dimethoxy-2-methyl-1,1-dioxo-1,2,3,4-tetrahydr...)
Affinity DataIC50:  38nMAssay Description:Inhibitory activity towards human calpain IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed