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BDBM50105345 CHEMBL3597259

SMILES: O=c1oc2ccccc2n1CCCCCCN1CCN(CCCn2c3ccccc3oc2=O)CC1

InChI Key: InChIKey=NWVFZRDTVIKKRV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105345   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nitric Oxide Synthase, inducible


(Mus musculus (mouse))
BDBM50105345
PNG
(CHEMBL3597259)
Show SMILES O=c1oc2ccccc2n1CCCCCCN1CCN(CCCn2c3ccccc3oc2=O)CC1
Show InChI InChI=1S/C27H34N4O4/c32-26-30(22-10-3-5-12-24(22)34-26)16-8-2-1-7-14-28-18-20-29(21-19-28)15-9-17-31-23-11-4-6-13-25(23)35-27(31)33/h3-6,10-13H,1-2,7-9,14-21H2
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a 4.50E+3n/an/an/an/an/an/a



Beni-Suef University

Curated by ChEMBL


Assay Description
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced iNOS activity incubated for 30 mins prior to LPS challenge me...


Bioorg Med Chem 23: 3248-59 (2015)


Article DOI: 10.1016/j.bmc.2015.04.057
BindingDB Entry DOI: 10.7270/Q26H4K5F
More data for this
Ligand-Target Pair