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BDBM50105462 CHEMBL81880::N,N,N',N'-Tetramethyl-acridine-3,6-diamine

SMILES: CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C

InChI Key: InChIKey=DPKHZNPWBDQZCN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50105462   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50105462
PNG
(CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...)
Show SMILES CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C
Show InChI InChI=1S/C17H19N3/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14/h5-11H,1-4H3
PDB

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KEGG

UniProtKB/SwissProt

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CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 1.22E+4n/an/an/an/an/an/a



University of Missouri

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)


Citation and Details
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50105462
PNG
(CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...)
Show SMILES CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C
Show InChI InChI=1S/C17H19N3/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14/h5-11H,1-4H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 1.22E+4n/an/an/an/an/an/a



University of Missouri

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against telomerase (Compound released from RNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)


Citation and Details
More data for this
Ligand-Target Pair
Telomerase reverse transcriptase


(Homo sapiens)
BDBM50105462
PNG
(CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...)
Show SMILES CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C
Show InChI InChI=1S/C17H19N3/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14/h5-11H,1-4H3
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 1.22E+4n/an/an/an/an/an/a



University of Missouri

Curated by ChEMBL


Assay Description
Inhibitory activity of the compound against telomerase (Compound released from DNA/DNA heteroduplex derivatized resin [sequence (TTAGGG)3)


Citation and Details
More data for this
Ligand-Target Pair