BDBM50105742 4-[4-(4-Fluoro-phenyl)-5-(2-methoxy-pyrimidin-4-yl)-imidazol-1-yl]-cyclohexanol::CHEMBL97162::trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)imidazole

SMILES: COc1nccc(n1)-c1c(ncn1[C@H]1CC[C@H](O)CC1)-c1ccc(F)cc1

InChI Key: InChIKey=ZQUSFAUAYSEREK-UHFFFAOYSA-N

Data: 2 KI  16 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50105742   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 13 (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 12 (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11 (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
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RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11 (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C alpha type (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>50	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>50	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 9 (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 2 (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>50	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>50	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase I isoform delta (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase I isoform alpha (Human)	BDBM50105742 (trans -1-(4-hydroxycyclohexyl)-4-(4-fluorophenyl)-...) Show SMILES Show InChI	GoogleScholar	UniChem		501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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