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BDBM50105939 3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-o-tolyl-1,5-dihydro-pyrazol-4-ylidene)-hydrazino]-naphthalene-1-sulfonic acid::CHEMBL122323

SMILES: Cc1[nH]n(-c2ccccc2C)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O

InChI Key: InChIKey=OZBDQEZQGQEWMU-UHFFFAOYSA-N

Data: 1 EC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105939   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thrombopoietin receptor


(Homo sapiens (Human))
BDBM50105939
PNG
(3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-o-tolyl-1,5-dihy...)
Show SMILES Cc1[nH]n(-c2ccccc2C)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O
Show InChI InChI=1S/C21H18N4O5S/c1-12-7-3-6-10-16(12)25-21(27)19(13(2)24-25)22-23-20-15-9-5-4-8-14(15)18(11-17(20)26)31(28,29)30/h3-11,24,26H,1-2H3,(H,28,29,30)
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PC cid
PC sid
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Similars

Article
PubMed
n/an/an/an/a 1.00E+4n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells


J Med Chem 44: 3730-45 (2001)


Article DOI: 10.1021/jm010283l
BindingDB Entry DOI: 10.7270/Q2MP52KF
More data for this
Ligand-Target Pair