BDBM50105939 3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-o-tolyl-1,5-dihydro-pyrazol-4-ylidene)-hydrazino]-naphthalene-1-sulfonic acid::CHEMBL122323

SMILES: Cc1[nH]n(-c2ccccc2C)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O

InChI Key: InChIKey=OZBDQEZQGQEWMU-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105939   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thrombopoietin receptor (Homo sapiens (Human))	BDBM50105939 (3-Hydroxy-4-[N'-(3-methyl-5-oxo-1-o-tolyl-1,5-dihy...) Show SMILES Cc1[nH]n(-c2ccccc2C)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O Show InChI InChI=1S/C21H18N4O5S/c1-12-7-3-6-10-16(12)25-21(27)19(13(2)24-25)22-23-20-15-9-5-4-8-14(15)18(11-17(20)26)31(28,29)30/h3-11,24,26H,1-2H3,(H,28,29,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells				J Med Chem 44: 3730-45 (2001) Article DOI: 10.1021/jm010283l BindingDB Entry DOI: 10.7270/Q2MP52KF
					More data for this Ligand-Target Pair