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BDBM50105947 3-Hydroxy-4-{N'-[3-methyl-5-oxo-1-(3-trifluoromethyl-phenyl)-1,5-dihydro-pyrazol-4-ylidene]-hydrazino}-naphthalene-1-sulfonic acid::CHEMBL125160

InChI string: InChI=1S/C21H15F3N4O5S/c1-11-18(20(30)28(27-11)13-6-4-5-12(9-13)21(22,23)24)25-26-19-15-8-3-2-7-14(15)17(10-16(19)29)34(31,32)33/h2-10,27,29H,1H3,(H,31,32,33)

SMILES: Cc1[nH]n(-c2cccc(c2)C(F)(F)F)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O

InChI Key: InChIKey=FFAVEPICBVBNIY-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50105947   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Thrombopoietin receptor


(Homo sapiens)
BDBM50105947
PNG
(3-Hydroxy-4-{N'-[3-methyl-5-oxo-1-(3-trifluorometh...)
Show SMILES Cc1[nH]n(-c2cccc(c2)C(F)(F)F)c(=O)c1N=Nc1c(O)cc(c2ccccc12)S(O)(=O)=O
Show InChI InChI=1S/C21H15F3N4O5S/c1-11-18(20(30)28(27-11)13-6-4-5-12(9-13)21(22,23)24)25-26-19-15-8-3-2-7-14(15)17(10-16(19)29)34(31,32)33/h2-10,27,29H,1H3,(H,31,32,33)
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PC sid
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Similars

AffyNet 
PubMed
n/an/an/an/a 40n/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Effective concentration for thrombopoietin luciferase activity was determined in BAF-3 cells


J Med Chem 44: 3730-45 (2001)

More data for this
Ligand-Target Pair