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BDBM50106215 CHEMBL3598108

SMILES: CS(=O)(=O)c1cnc(O[C@H]2CC[C@@H](CC2)OC2CCN(CC3(CC3)C(F)(F)F)CC2)cn1

InChI Key: InChIKey=ANIDPORIGUTQGM-WKILWMFINA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50106215   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucose-dependent insulinotropic receptor


(Rattus norvegicus)
BDBM50106215
PNG
(CHEMBL3598108)
Show SMILES CS(=O)(=O)c1cnc(O[C@H]2CC[C@@H](CC2)OC2CCN(CC3(CC3)C(F)(F)F)CC2)cn1
Show InChI InChI=1/C21H30F3N3O4S/c1-32(28,29)19-13-25-18(12-26-19)31-16-4-2-15(3-5-16)30-17-6-10-27(11-7-17)14-20(8-9-20)21(22,23)24/h12-13,15-17H,2-11,14H2,1H3/t15-,16-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 163n/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at rat GPR119 by HTRF cAMP assay


Bioorg Med Chem Lett 25: 3034-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.102
BindingDB Entry DOI: 10.7270/Q2SB47JS
More data for this
Ligand-Target Pair
G-protein coupled receptor 119 (GPR119)


(Homo sapiens (Human))
BDBM50106215
PNG
(CHEMBL3598108)
Show SMILES CS(=O)(=O)c1cnc(O[C@H]2CC[C@@H](CC2)OC2CCN(CC3(CC3)C(F)(F)F)CC2)cn1
Show InChI InChI=1/C21H30F3N3O4S/c1-32(28,29)19-13-25-18(12-26-19)31-16-4-2-15(3-5-16)30-17-6-10-27(11-7-17)14-20(8-9-20)21(22,23)24/h12-13,15-17H,2-11,14H2,1H3/t15-,16-
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 63n/an/an/an/a



Arena Pharmaceuticals

Curated by ChEMBL


Assay Description
Agonist activity at human GPR119 by HTRF cAMP assay


Bioorg Med Chem Lett 25: 3034-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.04.102
BindingDB Entry DOI: 10.7270/Q2SB47JS
More data for this
Ligand-Target Pair