BDBM50106326 CHEMBL3598153::US9550771, Example 30
SMILES OC(=O)C1CCN(CC1)c1nc(C(=O)c2c(Cl)cccc2C(F)(F)F)n2ccccc12
InChI Key InChIKey=GMKDGMOOAQPPOB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50106326
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of fluormone PPARgamma green from GST-tagged human PPARgamma-LBD after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 539nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Affinity DataEC50: 540nMAssay Description:Inverse agonist activity at N-terminal 6xHis-tagged human RORc ligand binding domain (241 to 486) expressed in bacterial expression system assessed a...More data for this Ligand-Target Pair