BDBM50106497 6-Chloro-7-(2-morpholin-4-yl-ethylamino)-quinoline-5,8-dione::6-chloro-7-(2-morpholinoethylamino)quinoline-5,8-dione::CHEMBL337173::NSC-663284

SMILES: Oc1c(Cl)c(N=CCN2CCOCC2)c(O)c2ncccc12

InChI Key: InChIKey=DWRQCWWWWDTWHB-UHFFFAOYSA-N

Data: 3 KI  20 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50106497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-lysine methyltransferase KMT5A (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
N-lysine methyltransferase KMT5A (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histone-lysine N-methyltransferase, H3 lysine-36 specific (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Replicase polyprotein 1ab (2019-nCoV)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Histone-lysine N-methyltransferase NSD3 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase, H3 lysine-36 specific (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase NSD2 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase NSD2 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase NSD2 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase NSD2 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 1 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase NSD2 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase NSD3 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase, H3 lysine-36 specific (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase NSD2 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 3 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 3 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
N-lysine methyltransferase KMT5A (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	<5.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
N-lysine methyltransferase KMT5A (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 3 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 1 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 3 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM50106497 (NSC-663284 | 6-Chloro-7-(2-morpholin-4-yl-ethylami...) Show SMILES Show InChI	GoogleScholar	UniChem		95	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair