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BDBM50106558 2-[(2-Benzyloxycarbonyl-propyl)-hydroxy-phosphinoylmethyl]-pentanedioic acid::CHEMBL132264

SMILES: CC(CP(O)(=O)CC(CCC(O)=O)C(O)=O)C(=O)OCc1ccccc1

InChI Key: InChIKey=NYUFUODXMXEYLV-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106558   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate carboxypeptidase II


(Rattus norvegicus)
BDBM50106558
PNG
(2-[(2-Benzyloxycarbonyl-propyl)-hydroxy-phosphinoy...)
Show SMILES CC(CP(O)(=O)CC(CCC(O)=O)C(O)=O)C(=O)OCc1ccccc1
Show InChI InChI=1/C17H23O8P/c1-12(17(22)25-9-13-5-3-2-4-6-13)10-26(23,24)11-14(16(20)21)7-8-15(18)19/h2-6,12,14H,7-11H2,1H3,(H,18,19)(H,20,21)(H,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 95n/an/an/an/an/an/a



Guilford Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against rat brain NAALADase (Folate hydrolase)


J Med Chem 44: 4170-5 (2001)


Article DOI: 10.1021/jm0001774
BindingDB Entry DOI: 10.7270/Q2D21WX8
More data for this
Ligand-Target Pair