BDBM50106635 (+/-)-2,3-bis(4-hydroxyphenyl)propanenitrile::2,3-Bis-(4-hydroxy-phenyl)-propionitrile::2,3-bis(4-hydroxyphenyl)propanenitrile::CHEMBL334773::DIARYLPROPIONITRILE

SMILES: c1cc(ccc1C[C@H](C#N)c2ccc(cc2)O)O

InChI Key: InChIKey=GHZHWDWADLAOIQ-UHFFFAOYSA-N

Data: 24 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50106635   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.39E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Estrogen receptor beta (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.710	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	16.7	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	876	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.30	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	304	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.70	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	208	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	66	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.850	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.660	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.820	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.90E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.20E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.10	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.90	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM50106635 (CHEMBL334773 | (+/-)-2,3-bis(4-hydroxyphenyl)propa...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair