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BDBM50106703 6-Hexylsulfanyl-3,4-diphenyl-pyridazine::CHEMBL137431

SMILES: CCCCCCSc1cc(-c2ccccc2)c(nn1)-c1ccccc1

InChI Key: InChIKey=OUABKTXLLXNPEI-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50106703   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50106703
PNG
(6-Hexylsulfanyl-3,4-diphenyl-pyridazine | CHEMBL13...)
Show SMILES CCCCCCSc1cc(-c2ccccc2)c(nn1)-c1ccccc1
Show InChI InChI=1S/C22H24N2S/c1-2-3-4-11-16-25-21-17-20(18-12-7-5-8-13-18)22(24-23-21)19-14-9-6-10-15-19/h5-10,12-15,17H,2-4,11,16H2,1H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.20E+4n/an/an/an/an/an/a



Università di Firenze

Curated by ChEMBL


Assay Description
In vitro acyl-coenzyme A:cholesterol acyltransferase inhibition in rat liver microsomes


J Med Chem 44: 4292-5 (2001)


Article DOI: 10.1021/jm010807h
BindingDB Entry DOI: 10.7270/Q2W37VMS
More data for this
Ligand-Target Pair