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BDBM50107043 CHEMBL321883::N-(4-Methoxy-benzoyl)-N'-(4-phenyl-butyl)-guanidine

SMILES: COc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1

InChI Key: InChIKey=DAXAEGQNFHDYBP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50107043   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 5 subunit alpha


(Homo sapiens (Human))
BDBM50107043
PNG
(CHEMBL321883 | N-(4-Methoxy-benzoyl)-N'-(4-phenyl-...)
Show SMILES COc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1
Show InChI InChI=1S/C19H23N3O2/c1-24-17-12-10-16(11-13-17)18(23)22-19(20)21-14-6-5-9-15-7-3-2-4-8-15/h2-4,7-8,10-13H,5-6,9,14H2,1H3,(H3,20,21,22,23)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.10E+3n/an/an/an/an/an/a



CeNeS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of sodium channel blockade in CHO cells expressing human cardiac (hHI) sodium channel


Bioorg Med Chem Lett 11: 3151-5 (2001)


Article DOI: 10.1016/s0960-894x(01)00644-8
BindingDB Entry DOI: 10.7270/Q2PC31P4
More data for this
Ligand-Target Pair
Voltage-gated sodium channel subunit alpha Nav1.2 (Nav1.2)


(Homo sapiens (Human))
BDBM50107043
PNG
(CHEMBL321883 | N-(4-Methoxy-benzoyl)-N'-(4-phenyl-...)
Show SMILES COc1ccc(cc1)C(=O)NC(N)=NCCCCc1ccccc1
Show InChI InChI=1S/C19H23N3O2/c1-24-17-12-10-16(11-13-17)18(23)22-19(20)21-14-6-5-9-15-7-3-2-4-8-15/h2-4,7-8,10-13H,5-6,9,14H2,1H3,(H3,20,21,22,23)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 820n/an/an/an/an/an/a



CeNeS Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of sodium channel blockade in CHO cells expressing neuronal mammalian type IIA (CNaIIA) sodium channel


Bioorg Med Chem Lett 11: 3151-5 (2001)


Article DOI: 10.1016/s0960-894x(01)00644-8
BindingDB Entry DOI: 10.7270/Q2PC31P4
More data for this
Ligand-Target Pair