BDBM50107647 CHEMBL140506::N-{1-[(Benzyloxymethyl-cyano-methyl)-carbamoyl]-2-m-tolyl-ethyl}-4-chloro-2-fluoro-benzamide

SMILES Cc1cccc(C[C@H](NC(=O)c2ccc(Cl)cc2F)C(=O)N[C@@H](COCc2ccccc2)C#N)c1

InChI Key InChIKey=MSEWXEHJUWCBHP-RDGATRHJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107647   

TargetCathepsin B(Homo sapiens (Human))
Novartis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50107647(CHEMBL140506 | N-{1-[(Benzyloxymethyl-cyano-methyl...)
Affinity DataIC50:  16.9nMAssay Description:Inhibitiory activity against recombinant human cathepsin B (cat B) expressed in baculovirus.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed