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BDBM50107674 Butyric acid 3-(5-methoxy-1H-indole-2-carbonyl)-phenyl ester::CHEMBL139665

SMILES: CCCC(=O)Oc1cccc(c1)C(=O)c1cc2cc(OC)ccc2[nH]1

InChI Key: InChIKey=FBHAIQXGJNLLRJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50107674   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tubulin


(Bos taurus)
BDBM50107674
PNG
(Butyric acid 3-(5-methoxy-1H-indole-2-carbonyl)-ph...)
Show SMILES CCCC(=O)Oc1cccc(c1)C(=O)c1cc2cc(OC)ccc2[nH]1
Show InChI InChI=1S/C20H19NO4/c1-3-5-19(22)25-16-7-4-6-13(10-16)20(23)18-12-14-11-15(24-2)8-9-17(14)21-18/h4,6-12,21H,3,5H2,1-2H3
PDB
MMDB

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Similars

Article
PubMed
n/an/a 850n/an/an/an/an/an/a



University of Regensburg

Curated by ChEMBL


Assay Description
Inhibition of tubulin polymerization.


J Med Chem 44: 4535-53 (2001)


Article DOI: 10.1021/jm010940+
BindingDB Entry DOI: 10.7270/Q2BZ65CN
More data for this
Ligand-Target Pair