BDBM50108076 (S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propionylamino)-3-methyl-butyrylamino]-3-methyl-pentanoylamino}-4-methylsulfanyl-butyric acid::2-{1-[1-(1-amino-2-sulfanylethylcarboxamido)-2-methylpropylcarboxamido]-2-methylbutylcarboxamido}-4-methylsulfanylbutanoic acid (Cys-Val-Ile-Met)::CHEMBL55423

SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CS)C(C)C)C(=O)N[C@@H](CCSC)C(O)=O

InChI Key InChIKey=WGRDTCQSCXOTES-YTFOTSKYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50108076   

LigandPNGBDBM50108076((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of FTase (unknown origin)-mediated K-Ras4B model peptide KKKKKKSK(Dans)TKCVIM farnesylation by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50108076((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibitory activity against bovine type-1 geranylgeranyl transferase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Bos taurus (bovine))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50108076((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...)
Affinity DataIC50:  165nMAssay Description:Inhibitory activity against Ras Farnesyl Protein transferase from bovine brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50108076((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...)
Affinity DataIC50:  340nMAssay Description:Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50108076((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...)
Affinity DataIC50:  250nMAssay Description:Inhibition of farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50108076((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50108076((S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propio...)
Affinity DataIC50:  200nMAssay Description:Inhibition of the FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed