BDBM50108300 CHEMBL38338::Indolocarbazole analogue
SMILES COC(=O)[C@@]1(O)C[C@H]2O[C@]1(C)n1c3ccc(CSCCN(C)C)cc3c3c4CNC(=O)c4c4c5cc(CSCCN(C)C)ccc5n2c4c13
InChI Key InChIKey=PXLLDBDHYSZSQP-GWAZHQGNSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50108300
TargetMitogen-activated protein kinase kinase kinase 9(Homo sapiens (Human))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of Mixed lineage kinase 1 (MLK1)More data for this Ligand-Target Pair
TargetProtein kinase C alpha/beta/delta/epsilon/eta/gamma/theta/zeta type(Rattus norvegicus)
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of NGF high affinity receptor tyrosine kinase TrkAMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
Kyowa Hakko Kogyo
Curated by ChEMBL
Kyowa Hakko Kogyo
Curated by ChEMBL
Affinity DataIC50: 123nMAssay Description:Inhibition of Mixed lineage kinase 3 (MLK3)More data for this Ligand-Target Pair