BDBM50108432 3-(2,5-Dimethoxy-phenyl)-1-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-1H-pyridin-2-one::CHEMBL64197

SMILES COc1ccc(OC)c(c1)-c1cccn(C(CN2CCCC2)c2ccccc2)c1=O

InChI Key InChIKey=HFYIORXUHHAYHO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50108432   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108432(3-(2,5-Dimethoxy-phenyl)-1-(1-phenyl-2-pyrrolidin-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity towards delta opioid receptor by the displacement of [125I]-DeltorphinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108432(3-(2,5-Dimethoxy-phenyl)-1-(1-phenyl-2-pyrrolidin-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Binding affinity towards mu opioid receptor by the displacement of [125I]-EnkephalinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D MöLndal

Curated by ChEMBL
LigandPNGBDBM50108432(3-(2,5-Dimethoxy-phenyl)-1-(1-phenyl-2-pyrrolidin-...)
Affinity DataIC50:  3.40nMAssay Description:Binding affinity towards kappa opioid receptor by the displacement of [125I]-(D-Pro10)-Dynorphin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed