BDBM50109085 (3-Azepan-1-yl-propyl)-benzo[1,3]dioxol-5-ylmethyl-[3-(3-nitro-phenyl)-isoxazol-5-yl]-amine::CHEMBL111109

SMILES [O-][N+](=O)c1cccc(c1)-c1cc([o+][n-]1)N(CCCN1CCCCCC1)Cc1ccc2OCOc2c1

InChI Key InChIKey=SUTYVKBDMFTKBS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50109085   

TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109085((3-Azepan-1-yl-propyl)-benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of secretion of radiolabeled serotonin from washed human platelets stimulated by 1 nM thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109085((3-Azepan-1-yl-propyl)-benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50:  830nMAssay Description:Displacement of [3H]-SFFLRR-NH2 from human thrombin receptor PAR-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50109085((3-Azepan-1-yl-propyl)-benzo[1,3]dioxol-5-ylmethyl...)
Affinity DataIC50:  1.02E+3nMAssay Description:Antagonistic activity against thrombin receptor, inhibition of secreted radiolabeled [3H]-5-HT from washed human platelets stimulated by 3 microM thr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed