BDBM50109526 CHEMBL3601862

SMILES [H][C@]12CS[C@@H](CCCCC(=O)NCCOCCOCCOCCn3cc(Nc4ncc(Cl)c(NCc5cccc(NC(=O)C=C)c5)n4)cn3)[C@@]1([H])NC(=O)N2

InChI Key InChIKey=GEFQQWLDJYHNNX-OLWNVYNHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50109526   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109526(CHEMBL3601862)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of JAK3 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109526(CHEMBL3601862)
Affinity DataIC50:  743nMAssay Description:Inhibition of JAK1 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109526(CHEMBL3601862)
Affinity DataIC50:  421nMAssay Description:Inhibition of JAK2 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50109526(CHEMBL3601862)
Affinity DataIC50:  3.12E+3nMAssay Description:Inhibition of TYK2 (unknown origin) by Z'-Lyte assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed